Synthesis of α-cyanato-α′-carbonyl sulfoxonium ylides in water.

Autor: Zhang, Qingyao, Luo, Cankun, Lai, Ruizhi, Lin, Zhiqian, Jia, Pengfei, Xu, Shuran, Guo, Li, Wu, Yong
Předmět:
Zdroj: Green Chemistry; 9/21/2023, Vol. 25 Issue 18, p7068-7072, 5p
Abstrakt: A new strategy for direct access to unreported α-cyanato-α′-carbonyl sulfoxonium ylides is reported. The developed open-flask operation is a catalyst-, metal- and additive-free green process, which has good compatibility with various substituents and generally excellent yields. This protocol can be applied to gram-scale production and modification of bioactive drugs which demonstrate the practicality of this method. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index