Clinical pregnancy in Turner syndrome following re-implantation of cryopreserved ovarian cortex.

Autor:	Dunlop, CE, Jack, SA, Telfer, EE, Zahra, S., Anderson, RA
Předmět:	TURNER'S syndrome PREMATURE ovarian failure FERTILITY preservation PREGNANCY INDUCED ovulation PATIENTS' families
Zdroj:	Journal of Assisted Reproduction & Genetics; Oct2023, Vol. 40 Issue 10, p2385-2390, 6p
Abstrakt:	Turner syndrome (TS) leads to a characteristic phenotype, including premature ovarian insufficiency and infertility. Ovarian tissue cryopreservation (OTC) is becoming an established fertility preservation strategy for both pre- and post-pubertal females and may offer the chance of having a biological family to selected patients with TS. To date, women with TS have had ovarian tissue cryopreserved but there are few reports of autologous re-implantation and none of pregnancy. We herein report, to our knowledge, the first clinical pregnancy in a patient with TS, conceived naturally following re-implantation of cryopreserved ovarian tissue which had been removed soon after spontaneous puberty. This provides proof of concept for OTC as a means of fertility preservation in TS. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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