| Abstrakt: |
Chronic wounds, which majorly consist of diabetic foot ulcers, pressure ulcers and venous leg ulcers, pose a challenge to all the wound care professionals around the globe as their healing process is erratic. These are generally characterized by prolonged inflammatory phase. A recent study has made it possible to identify the indicative, diagnostic and moreover, predictive biomarkers. The biomarkers collected for analysis are found in the fluids of wound like the wound exudate and serum and sample tissue from the wound. The currently employed techniques like Enzyme-Linked Immunosorbent Assay (ELISA) and Liquid Chromatography–Mass Spectrometry (LC–MS) holds disadvantages like cost-ineffectiveness, tedious and labour demanding nature. The Surface Enhanced Raman Spectroscopy (SERS) technique was applied in the monitoring and evaluation of wounds by using Cellulose fibre-based substrate. This specific substrate was found efficient and practical due to its advantages of being cheap, flexible and easy to use. Moreover, it can be employed as a point-of-care device readily available for diagnostic purposes. [ABSTRACT FROM AUTHOR] |
