| Abstrakt: |
Methyl (3-Chloro-5-bromophenyl)carbamate (3n) Compound B 3n b was obtained from the reaction of 3-chloro-5-bromoaniline (62.0 mg, 0.3 mmol) and carbazate B 2a b (1.5 mmol, 3.0 equiv), and purified by column chromatography (10:1 PE/EtOAc). Methyl (3-Chloro-5-methylphenyl)carbamate (3o) Compound B 3o b was obtained from the reaction of 3-chloro-5-methylaniline (42.3 mg, 0.3 mmol) and carbazate B 2a b (1.5 mmol, 3.0 equiv), and purified by column chromatography (10:1 PE/EtOAc). Methyl (4-Methoxyphenyl)carbamate (3h) 29 Compound B 3h b was obtained from the reaction of 4-methoxyaniline (36.9 mg, 0.3 mmol) and carbazate B 2a b (1.5 mmol, 3.0 equiv), and purified by column chromatography (5:1 PE/EtOAc). Keywords: metal-free C-N coupling; one-pot synthesis; mild conditions EN metal-free C-N coupling one-pot synthesis mild conditions 3113 3120 8 09/11/23 20231004 NES 231004 Graph Carbamates are widely utilized as substrates in a variety of drugs and organic syntheses. [Extracted from the article] |
