Clinical and Serological Characteristics of Ocular Toxoplasmosis in the Democratic Republic of Congo.

Autor: Nsiangani Lusambo, Nadine, Kaimbo Wa Kaimbo, Dieudonné, Mumba Ngoyi, Dieudonné, Kilangalanga Ngoy, Janvier, Ngoyi Bambi, Marie-Thérèse, Kadima Mutombo, Théodore, Kintoki Makela, Guy, Ngandowe Nzamokili, Lady, de-la-Torre, Alejandra
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Zdroj: Ocular Immunology & Inflammation; Sep2023, Vol. 31 Issue 7, p1522-1527, 6p
Abstrakt: To describe demographic data, clinical features, and serological profiles in a cohort of Congolese patients with ocular toxoplasmosis (OT). Cross-sectional study, carried out between March 2020 and July 2021 in two ophthalmic clinics in Kinshasa. The study comprised 95 participants with OT. Fifty-three patients were male (55.8%). The mean age at presentation was 35.6 ± 14.1 years (range 8–69 years); 71 had active OT (74.7%), among them, 33 had primary OT (46.5%), and 38 had recurrences (53.5%). At presentation, 51 patients (53.7%) had visual impairment (VA < 6/18). Retinochoroidal lesions were located in the central retina in 60 patients (63.1%). Patients with primary OT tend to have higher IgG levels than those with recurrent OT (P =.01). We report the largest cohort of patients with OT in sub-Saharan Africa. In our setting, most patients had recurrent OT with multiple, extensive, and central retinochoroidal lesions. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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