Bronchiolitis Due to RSV and HMPV—Epidemiology, Clinical Course, and Prognosis: Experience of a Single Tertiary Center.
| Autor: | Azar, Bar, Hashavya, Saar, Ohana Sarna Cahan, Lea, Reif, Shimon, Gross, Itai |
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| Předmět: |
METABOLISM in RNA viruses
RESPIRATORY syncytial virus C-reactive protein INTENSIVE care units LENGTH of stay in hospitals ACADEMIC medical centers ASTHMA CHEST X rays ALBUTEROL ADRENALINE AGE distribution HOSPITAL care of newborn infants PEDIATRICS TERTIARY care ACQUISITION of data FISHER exact test IMMUNOSUPPRESSION RETROSPECTIVE studies PATIENTS BRONCHITIS SEVERITY of illness index TREATMENT effectiveness COMPARATIVE studies HOSPITAL admission & discharge SEASONS MEDICAL records CHI-squared test DESCRIPTIVE statistics CYANOSIS OXYGEN therapy ELECTRONIC health records DATA analysis software HYPERTONIC saline solutions DISEASE complications CHILDREN |
| Zdroj: | Clinical Pediatrics; Oct2023, Vol. 62 Issue 9, p1032-1039, 8p |
| Abstrakt: | Acute bronchiolitis is a leading cause of hospitalization in infants. In this retrospective study, 645 patients with acute bronchiolitis diagnosed as respiratory syncytial virus (RSV; n = 538) or human metapneumovirus (HMPV; n = 107) were compared in terms of demographic, clinical, and laboratory findings. The HMPV patients presented later in the winter, were older (20 vs 7.55 months; P <.001)), had higher levels of C-reactive protein (4.55 vs 3.03 mg/dL; P =.007), and a higher prevalence of complications (43.9% vs 32.7%; P =.03). This study highlights the similarities and differences between these 2 common respiratory viral pathogens and shows that HMPV has a slightly more severe disease course than RSV. These findings can help guide approaches to these 2 common viruses that cause bronchiolitis. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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