| Autor: |
Mann, N. S., Borkar, B. B., Narenderan, K. P., Kadian, R. S., Mann, S. K., Martin, R. L. |
| Předmět: |
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| Zdroj: |
American Journal of Gastroenterology (Springer Nature); Aug1979, Vol. 72 Issue 2, p141-145, 5p, 1 Chart, 1 Graph |
| Abstrakt: |
Colonic pH was continuously monitored by a pH electrode implanted in the transverse colon of rats over a 24-hour period. Lactulose significantly reduced the colonic pH to 5.37 ± .39 from a fasting value of 6.77 ± .75. Pretreatment with neomycin or concomitant use of a nonabsorbable antacid prevented lactulose-induced reduction in the colonic pH. The clinical implication of the study is that combined use of lactulose with neomycin or high doses of non-absorbable antacids in the treatment of chronic portasystemic encephalopathy may be undesirable. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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