Fatal Rapidly Progressive Interstitial Pneumonitis Associated With Amyopathic Dermatomyositis and CD8 T Lymphocytes.

Autor: Yokoyama, Toshinobu, Sakamoto, Teruo, Shida, Norihiko, Kinoshita, Masaharu, Kunou, Yoshifumi, Karukaya, Ritsuko, Takamatsu, Manabu, Aizawa, Hisamichi
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Zdroj: Journal of Intensive Care Medicine; May/Jun2005, Vol. 20 Issue 3, p160-163, 4p
Abstrakt: A patient with amyopathic dermatomyositis associated with fatal rapidly progressive interstitial pneumonitis resistant to therapy is described. Pathologic examination of a transbronchial lung biopsy specimen showed diffuse alveolar damage and nonspecific interstitial pneumonia-organizing pneumonia-like findings. Bronchoalveolar lavage fluid contained many CD8+ lymphocytes, considered to be cytotoxic T cells. Analysis of bronchoalveolar lavage fluid in this case may provide prognostically and pathogenetically important information. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index