| Autor: |
Löffler, Philipp M. G., Risgaard, Nikolaj A., Svendsen, Bettina L., Jepsen, Katrine A., Rabe, Alexander, Vogel, Stefan |
| Předmět: |
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| Zdroj: |
Chemical Communications; 9/11/2023, Vol. 59 Issue 70, p10548-10551, 4p |
| Abstrakt: |
Assembly and fusion between different populations of lipid nanoparticles was mediated by membrane-anchored lipidated nucleic acid (LiNA) strands and observed using surface plasmon resonance (SPR) as a label-free real-time assay. Irreversible membrane fusion was distinguished from reversible assembly by enzymatical cleavage of dsDNA tethers in situ. The assay enables user-friendly monitoring and application of membrane fusion in the context of liposomal drug delivery or synthetic biology. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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