| Autor: |
Tuchiu, Bianca-Maria, Stefan-van Staden, Raluca-Ioana, van Staden, Jacobus Frederick, Aboul-Enein, Hassan Y. |
| Předmět: |
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| Zdroj: |
Chemosensors; Aug2023, Vol. 11 Issue 8, p446, 12p |
| Abstrakt: |
A disposable stochastic platform based on calix [6]arene modified multi-walled carbon nanotubes-gold nanoparticles screen-printed electrode has been developed for the simultaneous determination of calcipotriol and betamethasone. For both analytes, very wide linear concentration ranges and extremely low limits of quantification (LOQ) were obtained: from 1.0 × 10−15 to 1.0 × 10−3 mol L−1 and with a 1.0 × 10−15 mol L−1 LOQ for calcipotriol, and from 1.0 × 10−16 to 1.0 × 10−2 mol L−1 with a 1.0 × 10−16 mol L−1 LOQ for betamethasone. The applicability of the sensing platform was successfully tested in commercially available topical pharmaceutical gel and surface water samples, obtaining recovery values ranging from 99.10 to 99.99% and relative standard deviation values under 0.05%. The obtained results render the proposed platform a viable, robust, selective, and sensitive tool that can be employed for the determination of the analytes in on-site routine quality control of pharmaceuticals and water quality monitoring. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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