| Autor: |
Lai, Xuhui, Guo, Jinhu, Zhang, Xuelian, Wang, Honghai |
| Předmět: |
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| Zdroj: |
FEMS Microbiology Letters; May2005, Vol. 246 Issue 1, p87-90, 4p |
| Abstrakt: |
Abstract: We report here the identification of a novel domain ¿ DIM (N-terminal domain in bacterial membrane proteins and other proteins) present exclusively in bacterial species including mycobacteria, revealed by PSI-BLAST iterative searches. DIM comprises about 53 amino acids in length with conserved Leu, Ile and Gly residues. Secondary structure prediction indicated that this domain contains two a-helices. DIM occurs at the N-terminus of proteins, and was found particularly but not exclusively in proteins with a transmembrane domain, and also in proteins with a FHA domain or RPT repeats. DIM-containing proteins have been reported to be involved in pathogenicity, signal transduction or small solute transport. [Copyright &y& Elsevier] |
| Databáze: |
Complementary Index |
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