Autor: |
Gordienko, Lyubov, Kulikova, Elena, Novikov, Artem |
Předmět: |
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Zdroj: |
AIP Conference Proceedings; 2023, Vol. 3011 Issue 1, p1-5, 5p |
Abstrakt: |
The paper presents data on the nature of post-vaccination reactions in cattle immunized with a vaccine from a weakly agglutinogenic B. abortus 82 strain. The work was carried out from 2017 to 2022. on a farm recovered from brucellosis. Since the farm is located in a threatened area, the entire cattle population was subjected to immunization with reimmunization of cows every 24 months. Routine serological studies were performed every six months using standard S-diagnosticums and experimental samples made from Brucella homologous to the vaccine strain used. It has been established that in some animals specific antibodies to Brucella can persist in the blood serum for more than 6 months. In most of the reacting animals, immunoglobulins were detected in the minimum diagnostic titers (CFR 1:5++-1:10++). It was noted that during the entire period of observation in serological reactions, the activity of complement-fixing antibodies was significantly higher with the R-brucella antigen than with the standard (S-) antigen. The use of an antigen made from dissociated forms of Brucella made it possible to differentiate post-vaccination reactions. As a result of the studies, it was noted that with repeated immunization of cattle with a vaccine from the B. abortus 82 strain with periodic revaccination of cows, the number of reacting animals decreased dynamically [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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