Incidence of Post Total Laryngectomy Hypothyroidism: Effects of Thyroid Gland Surgery and Post-Operative Radiotherapy.

Autor:	Nassar, Ahmed Amin, Shoaib, Abdelrahman Ahmed, Dewidar, Hazem Mohammed, Azooz, Khaled Omar
Předmět:	LARYNGECTOMY THYROID gland HYPOTHYROIDISM RADIOTHERAPY HEMITHYROIDECTOMY NECK dissection
Zdroj:	Indian Journal of Otolaryngology & Head & Neck Surgery; Sep2023, Vol. 75 Issue 3, p1336-1343, 8p
Abstrakt:	To record the incidence of hypothyroidism in patients after total laryngectomy, whether with or without postoperative radiation therapy and to analyze the effect of hemithyroidectomy for the development of hypothyroidism. A retrospective study included patients who underwent total laryngectomy (with or without hemithyroidectomy) between 2018 and 2021 for laryngeal carcinoma and/or received postoperative radiotherapy. Thirty-six (45%) of the 80 enrolled patients developed hypothyroidism after a median follow-up of 16 months. In this study, adjuvant radiation and central neck dissection were found to be significantly linked with developing post-operative hypothyroidism (p values: 0.001, 0.007, respectively). The incidence of hypothyroidism in patients treated for laryngeal carcinoma is high, especially after combination treatment of surgery and radiotherapy. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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