Silver-catalyzed pyrazole migration and cycloaddition reaction of diazo pyrazoleamides with ketimines.

Autor: Shi, Maoqing, Niu, Gejun, Zhang, Tianyuan, Xu, Aimin, Zheng, Rimei, Yusuf, Abdulla, Shi, Taoda, Hu, Wenhao, Qian, Yu
Předmět:
Zdroj: Chemical Communications; 9/4/2023, Vol. 59 Issue 68, p10311-10314, 4p
Abstrakt: A novel pyrazole migration and cycloaddition process is well developed via AgOTf-catalyzed annulation reactions of α-diazo pyrazoleamides with ketimines. This protocol discloses efficient access to synthesize a series of spirooxindole-based β-lactams in good to excellent yields and the diastereoselectivity is switchable by tuning the substituents on the α-diazo pyrazoleamides. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index