Central South University Reports Findings in Lymphoid Leukemia (A semi-mechanistic pharmacokinetic/pharmacodynamic model for alanine aminotransferase-based hepatotoxicity of methotrexate in paediatric patients with acute lymphoid leukemia).

Předmět:	LYMPHOCYTIC leukemia CHILD patients ACUTE leukemia PHARMACOKINETICS ALANINE
Zdroj:	Pediatrics Week; 8/25/2023, p100-100, 1p
Abstrakt:	Keywords: Changsha; People's Republic of China; Asia; Alanine; Amino Acids; Aminotransferase; Antimetabolites; Antineoplastics; Antipsoriatics; Antirheumatics; Cancer; Drugs and Therapies; Enzymes and Coenzymes; Gastroenterology; Health and Medicine; Hematology; Leukemia; Lymphoid Leukemia; Lymphoproliferative Disorders; Methotrexate Therapy; Oncology; Pediatrics; Pharmaceuticals; Pharmacodynamics; Pharmacokinetics; Pharmacology EN Changsha People's Republic of China Asia Alanine Amino Acids Aminotransferase Antimetabolites Antineoplastics Antipsoriatics Antirheumatics Cancer Drugs and Therapies Enzymes and Coenzymes Gastroenterology Health and Medicine Hematology Leukemia Lymphoid Leukemia Lymphoproliferative Disorders Methotrexate Therapy Oncology Pediatrics Pharmaceuticals Pharmacodynamics Pharmacokinetics Pharmacology 100 100 1 08/21/23 20230825 NES 230825 2023 AUG 26 (NewsRx) -- By a News Reporter-Staff News Editor at Pediatrics Week -- New research on Oncology - Lymphoid Leukemia is the subject of a report. MTX concentrations were assessed at 24-hour intervals until the concentration dropped below 0.1 mmol/L. ALT concentrations were measured both before and after MTX administration. [Extracted from the article]
Databáze:	Complementary Index
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