| Autor: |
Kotipalli, Ramesh, Babu, Undamatla Suri, Nanubolu, Jagadeesh Babu, Reddy, Maddi Sridhar |
| Předmět: |
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| Zdroj: |
Chemical Communications; 8/28/2023, Vol. 59 Issue 67, p10137-10140, 4p |
| Abstrakt: |
Selective annulations of alkynes represent a powerful tool for constructing multicyclic scaffolds while installing desired substitution patterns with precision. Herein, we report a Rh-catalyzed unique annulation of indolyl oxopropanenitrile with hydroxy-alkynoates to access pyranoindole cyclic motifs, featuring enol oxygen as a rare chemoselective reactive terminal. The reaction proceeds via a five-membered oxy-rodacycle through C–H activation by a rhodium complex guided by enolic- and propargyloxy dual co-ordination to enable a regio- and stereoselective modular assembly. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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