| Autor: |
Gaharwar, Rakesh, Dubey, Dinkar, Sharma, Sudhanashu, Mudgal, Nitesh |
| Předmět: |
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| Zdroj: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2023, Vol. 14 Issue 7, p1538-1542, 5p |
| Abstrakt: |
Background & Method: The aim of the study is to study the renal functions in Adult HIV patients taking first line HAART initiation using estimated Glomerular Filtration Rate (eGFR). The 100 newly diagnosed HIV positive patients were included in the study. Detailed history – including duration of disease, any past history of antiretroviral drug and other medications, treatment regimen started, WHO staging of the HIV disease were obtained . Result: Out of 100 patients, at the end of study 21% patients with Normal GFR (>90), 34% with mild reduction (60-90) and 45% with moderate to severe reduction in eGFR (<60), 10 months after initiating ART, with majority of GFR decline in Tenofovir based regimens. The patients were distributed in all the clinical stages of HIV disease from T1 to T4.Majority of HIV patients were in WHO clinical stage T1 (61%) followed byT4(15%) and 12% T2 & T3 respectively. Conclusion: This study signifies that Tenofovir based regimen is the basis for most of the decline in renal function in patients on ART. Renal dysfunction is highly prevalent in the study population. The mean age of presentation in our study population was 40.70 years. There is significant correlation between age and eGFR. In our study 44 % are females, 56% are male. The difference of average in eGFR between male and female is not statistically significant. Mean weight is 49 Kg. No significant correlation between weight and decline in eGFR. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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