Effects of traditional and novel proteolytic agents on tissue dissolution and dentine microhardness.

Autor: Jacob, Shwetha Elizabeth, Prasad, Niharika, Dutta, Sreya, Kumblekar, Vasavi, Natarajan, Srikant, Jayaprakash, Kukkila, Thomas, Manuel Sebastian
Předmět:
Zdroj: Australian Endodontic Journal; Aug2023, Vol. 49 Issue 2, p287-294, 8p
Abstrakt: The study aimed to evaluate the tissue‐dissolving ability of papain and bromelain with respect to that of sodium hypochlorite (NaOCl) at the temperatures of 25°C and 60°C. The study also assessed the effects of these proteolytic agents on radicular dentine microhardness. Warming NaOCl, papain and bromelain solutions resulted in significant tissue dissolution at all time intervals (p < 0.001). At 60°C, bromelain showed significantly higher tissue weight loss at every time interval when compared to NaOCl (p < 0.001). All of the three organic tissue dissolvents reduced the microhardness at 1 hr when compared to their respective baseline values. The reduction in microhardness from the baseline reading was statistically significant only in the papain group at 30 min (p = 0.018) and at 60 min (p = 0.03) when compared to the control group. Hence it was concluded that bromelain exerted superior tissue dissolution action, especially when warmed, with minimal effect on dentine microhardness. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index