DeepBLS: Deep Feature-Based Broad Learning System for Tissue Phenotyping in Colorectal Cancer WSIs.

Autor:	Baidar Bakht, Ahsan, Javed, Sajid, Gilani, Syed Qasim, Karki, Hamad, Muneeb, Muhammad, Werghi, Naoufel
Předmět:	TISSUE analysis DEEP learning SMOOTH muscle CELL physiology MOLECULAR pathology LABORATORIES COLORECTAL cancer LYMPHOCYTES RESEARCH funding DESCRIPTIVE statistics AUTOMATION HISTOLOGY STATISTICAL models PHENOTYPES ALGORITHMS TUMOR grading
Zdroj:	Journal of Digital Imaging; Aug2023, Vol. 36 Issue 4, p1653-1662, 10p, 2 Color Photographs, 2 Diagrams, 4 Charts, 1 Map
Abstrakt:	Tissue phenotyping is a fundamental step in computational pathology for the analysis of tumor micro-environment in whole slide images (WSIs). Automatic tissue phenotyping in whole slide images (WSIs) of colorectal cancer (CRC) assists pathologists in better cancer grading and prognostication. In this paper, we propose a novel algorithm for the identification of distinct tissue components in colon cancer histology images by blending a comprehensive learning system with deep features extraction in the current work. Firstly, we extracted the features from the pre-trained VGG19 network which are then transformed into mapped features space for nodes enhancement generation. Utilizing both mapped features and enhancement nodes, the proposed algorithm classifies seven distinct tissue components including stroma, tumor, complex stroma, necrotic, normal benign, lymphocytes, and smooth muscle. To validate our proposed model, the experiments are performed on two publicly available colorectal cancer histology datasets. We showcase that our approach achieves a remarkable performance boost surpassing existing state-of-the-art methods by (1.3% AvTP, 2% F1) and (7% AvTP, 6% F1) on CRCD-1, and CRCD-2, respectively. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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