Remediation of cognitive and motor functions in Tunisian elderly patients with mild Alzheimer's disease: implications of music therapy and/or physical rehabilitation.
Autor: | Chéour, Sarah, Chéour, Chouaieb, Gendreau, Tommy, Bouazizi, Majdi, Singh, Kumar Purnendu, Saeidi, Ayoub, Dan Tao, Supriya, Rashmi, Bragazzi, Nicola Luigi, Baker, Julien S., Chéour, Foued |
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Předmět: |
ALZHEIMER'S disease treatment
WALKING speed MILD cognitive impairment PHYSICAL therapy GAIT in humans COGNITION PSYCHOLOGY of movement REHABILITATION of Alzheimer's patients MUSIC therapy RANDOMIZED controlled trials COMPARATIVE studies TREATMENT effectiveness WALKING DIAGNOSIS DESCRIPTIVE statistics RESEARCH funding QUESTIONNAIRES COMBINED modality therapy STATISTICAL sampling DATA analysis software OLD age |
Zdroj: | Frontiers in Aging Neuroscience; 2023, p1-11, 11p |
Abstrakt: | The purpose of this study was to compare the effects of music therapy (MT) and/or physical rehabilitation (PR) on cognitive and motor function in elderly Tunisian male and female patients with mild Alzheimer's disease (AD). Male patients (N: 16; age: 74.19 ± 4.27 years; weight: 76.71 ± 5.22 kg) and female patients (N: 12; age: 71.46 ± 3.36 years; weight: 67.47 ± 4.31 kg) with mild AD were randomly assigned into 4 groups including control group (Co), PR group participated in physical rehabilitation, MT group received music therapy and MT + PR received both music therapy and physical rehabilitation. Participants were required to engage in the study for four months with three 60-min sessions per week. We found all scores of cognitive (MMSE, ADAS-Cog Total and the ADAS-Cog Memory subscale) and motor functions (step length, walking speed, 6MVT and BBS score) evaluated were the greatest in MT + PR compared to the other groups. Our study also demonstrated that MT has a greater effect on cognitive function, while PR has a more pronounced effect on motor function. Changes in MMSE scores were significantly positively correlated in the PR, MT and MT + PR groups with improvements in all motor functions including step length (r = 0.77), walking speed (r = 0.73), 6MVT (r = 0.75) and BBS scores (r = 0.78) in AD patients. In conclusion, the combination of MT and PR seems to be an appropriate intervention approach that needs consideration as a treatment strategy for elderly male and female patients with mild AD. [ABSTRACT FROM AUTHOR] |
Databáze: | Complementary Index |
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