A case of squamous cell carcinoma of the breast achieved a pathological complete response after dose-dense AC + dose-dense PTX.

Autor: Araki, Misato, Matsui, Koshi, Takagi, Kohji, Kanaya, Emi, Sekine, Shinichi, Nagasawa, Shiho, Watanabe, Toru, Miwa, Takeshi, Hirano, Katsuhisa, Igarashi, Takamichi, Tanaka, Haruyoshi, Shibuya, Kazuto, Hashimoto, Isaya, Hojo, Shozo, Yoshioka, Isaku, Okumura, Tomoyuki, Hirabayashi, Kenichi, Fujii, Tsutomu
Předmět:
Zdroj: Surgical Case Reports; 8/2/2023, Vol. 9 Issue 1, p1-5, 5p
Abstrakt: Background: Squamous cell carcinoma (SCC) of the breast is a rare form of breast cancer, accounting for approximately 0.1% of all breast cancers. It is known for its rapid tumor growth and poor prognosis with no established treatment. Case presentation: A 56-year-old woman was diagnosed with breast SCC with axillary, supraclavicular and internal thoracic lymph node metastases. She received neoadjuvant chemotherapy (NAC) with dose-dense doxorubicin and cyclophosphamide (AC) followed by dose-dense paclitaxel (PTX). This treatment resulted in a pathological complete response (pCR) after breast-conserving surgery. The patient was then treated with radiotherapy. She remained free of recurrence for three years postoperatively. Conclusions: We report a rare case of breast SCC treated with preoperative dose-dense chemotherapy, resulting in pCR and allowing breast-conserving surgery. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index