Virulence factors, antimicrobial resistance and phylogeny of bovine mastitis-associated Streptococcus dysgalactiae.

Autor: Crippa, Bruna Lourenço, Rodrigues, Marjory Xavier, Tomazi, Tiago, Yang, Yongqiang, de Oliveira Rocha, Liliana, Bicalho, Rodrigo Carvalho, Silva, Nathália Cristina Cirone
Předmět:
Zdroj: Journal of Dairy Research; May2023, Vol. 90 Issue 2, p152-157, 6p
Abstrakt: We carried out a thorough genetic evaluation of Streptococcus dysgalactiae isolated from clinical bovine mastitis cases and performed a phylogenetic analysis to represent the evolutionary relationship between S. dysgalactiae sequences. A total of 35 S. dysgalactiae strains were isolated from cases of clinical mastitis identified at a large commercial dairy farm located near Ithaca, New York. Whole-genome sequencing identified twenty-six antibiotic resistance genes, four of which were acquired genes, in addition to fifty virulence genes. Multi-locus sequence typing detected three new sequence types (STs). We conclude that a high proportion of this microorganism carries multiple virulence determinants and resistance genes, and that this indicates its potential to cause mastitis. Eight different STs were identified, of which ST453 (n = 17) was the most prevalent and ST714, ST715, ST716 were novel STs. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index