| Autor: |
Solórzano Álava, Luis, Bedoya Pilozo, Cesar, Hernandez Alvarez, Hilda, Rojas Rivera, Lazara, Rodriguez Ortega, Misladys, Fraga Nodarse, Jorge, Pereira, Leandro de Mattos, Simões, Raquel de Oliveira, Vilela, Roberto do Val |
| Předmět: |
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| Zdroj: |
Pathogens; Jul2023, Vol. 12 Issue 7, p878, 13p |
| Abstrakt: |
The nematode Angiostrongylus cantonensis has been reported worldwide. However, some basic questions remain unanswered about A. cantonensis in Ecuador: (1) Was the invasion of A. cantonensis in Ecuador unique, or did it occur in different waves? (2) Was this invasion as recent as historical records suggest? (3) Did this invasion come from other regions of South America or elsewhere? To address these issues, we assessed the genetic diversity of MT-CO1 gene sequences from isolates obtained in 11 of Ecuador's 24 provinces. Our Bayesian inference phylogenetic tree recovered A. cantonensis as a well-supported monophyletic group. All 11 sequences from Ecuador were identical and identified as AC17a. The haplotype AC17a, found in Ecuador and the USA, formed a cluster with AC17b (USA), AC13 (Thailand), and AC12a-b (Cambodia). Notably, all the samples obtained in Ecuadorian provinces' different geographic and climatic regions had no genetic difference. Despite the lack of genetic information on A. cantonensis in Latin America, except in Brazil, our finding differs from previous studies by its absence of gene diversity in Ecuador. We concluded that the invasion of A. cantonensis in Ecuador may have occurred: (1) as a one-time event, (2) recently, and (3) from Asia via the USA. Further research should include samples from countries neighboring Ecuador to delve deeper into this. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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