| Autor: |
Cheruvanachari, Priya, Mishra, Monika, Pattnaik, Subhaswaraj, Naik, Pradeep Kumar |
| Předmět: |
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| Zdroj: |
Biologia; Aug2023, Vol. 78 Issue 8, p2253-2260, 8p |
| Abstrakt: |
The Kewda essential oil (KEO) extracted from Pandanus odorifer male flower was evaluated for its phytochemical profiles, antimicrobial and anti-biofilm activities against Staphylococcus aureus and Klebsiella pneumoniae and their reference strains, MTCC 740 and MTCC 109 respectively. As evident from GC-MS analysis, the phytochemical profiles revealed the presence of 2-phenyl ethyl methyl ether (PEME) and Terpinen-4-ol as prominent secondary metabolites. The MIC of KEO was 5% (v/v) against all the test bacteria. The KEO exhibited strong antibacterial and anti-biofilm activities against test bacteria. A significant reduction in the biofilm production was observed with an inhibition of 67.51 ± 1.29% and 61.17 ± 3.75% against K. pneumoniae and 71.76 ± 4.56% and 59.3 ± 6.24% against S. aureus. The light and fluorescence microscopic analysis confirmed a significant decrease in the density and thickness of the biofilm matrix against both the clinical and reference strains when treated with sub-MIC of KEO. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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