Autor: |
Miron, Dan, Brosilow, Sharon, Felszer, Klari, Reich, Dan, Halle, David, Wachtel, Daniel, Eidelman, Arthur I., Schlesinger, Yechiel |
Předmět: |
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Zdroj: |
Journal of Perinatology; May2005, Vol. 25 Issue 5, p299-303, 5p |
Abstrakt: |
OBJECTIVES:: To determine the incidence and clinical manifestations of human breast milk (HMB)-associated acquired cytomegalovirus (CMV) infection in small premature infants. STUDY DESIGN:: A prospective study of premature infants born at or prior to 32 weeks gestation, and or infants weighing 1500?g or less at birth. The babies were divided into two groups: Group 1 included babies of CMV seropositive mothers who received HBM throughout the study period. Group 2 included babies of seronegative mothers or babies that did not receive HBM at all. Urine sample were obtained once weekly from birth until the age of 8 weeks or until discharge and were tested for the presence of CMV-DNA by PCR. RESULTS:: Four of 70 infants from group 1 (5.7%, 95%CI, 0 to 11%) acquired CMV infection between the ages of 3 and 7 weeks as compared to none of 26 babies in group 2. Only one infected baby had severe CMV disease with complete recovery. CONCLUSION:: The relative incidence of HBM-associated CMV infection and the severity of HBM-associated CMV disease in premature infants are low.Journal of Perinatology (2005) 25, 299-303. doi:10.1038/sj.jp.7211255 Published online 27 January 2005 [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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