CAROTID SINUS NERVE STIMULATION: STUDIES ON THE MECHANISM OF THE HYPOTENSIVE RESPONSE.

Autor: Drews, John A., Stansel Jr., H. C., Glenn, William W. L.
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Zdroj: Vascular Surgery; Jun1968, Vol. 2 Issue 2, p78-87, 10p, 6 Graphs
Abstrakt: Carotid sinus nerve stimulation, through direct wires from an attached power source or by radiofrequency induction, was studied in dogs which were normotensive, dogs with acute hypertension from bilateral carotid artery ligation, and dogs with chronic hypertension from created stenosis of the renal arteries. The blood pressure and heart rate were reduced to a greater extent in the hypertensive animals as compared to the normotensives. There was no significant difference between the response of the blood pressure to stimulation applied to each nerve singly, or to both nerves simultaneously, but there was a suggestion that response to right nerve stimulation was greater. The heart rate dropped to a considerably lower level when both nerves were stimulated simultaneously. The cardiac output and total peripheral resistance fell during stimulation in all three groups of animals. As renal blood flow is probably diminished during carotid sinus nerve stimulation, great caution must be exercised in using this method of reducing blood pressure in patients with renal disease. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index