Negative nanopore sequencing for mapping biochemical processes on DNA molecules.

Autor: Kim, YoonYi, Noh, Chanyoung, Yu, Myungheon, Bae, Minji, Jo, Kyubong
Předmět:
Zdroj: Chemical Communications; 8/7/2023, Vol. 59 Issue 61, p9388-9391, 4p
Abstrakt: Nanopore sequencing maps biochemical processes on DNA by detecting negative peaks in the sequence alignment profile. Protein-bound DNA and single-strand broken DNA cannot pass through nanopores, resulting in unaligned regions in the genome MAP. This novel approach provides a clear representation of genomic biochemical events. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index