Study of autonomic nervous dysfunction in patients of diabetes mellitus and its relations with the duration of disease.

Autor: Arora, Meena, Arora, Rajiv, Singh, Parminder, Khanna, Gagan
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2022, Vol. 13` Issue 8, p1103-1107, 5p
Abstrakt: Background: Diabetes is most common amongst the endocrine and metabolic disorders. It is chronic disorder of carbohydrate, fat and protein metabolism attributed to either diminished production of insulin or resistance to its actions. Diabetes is known to produce microvascular and macrovascular changes in the body leading to various complications like diabetic nephropathy and diabetic retinopathy. Involvement of nervous system (neuropathy) is also a well-established complication in diabetic patients. Amongst the neuropathies associated with diabetes, involvement of autonomic nervous system has been found by many researchers. Aim: Our study is aimed at finding relationship of autonomic neuropathy with the duration of the disease in diabetes. The present study was conducted on 100 patients in 4 different groups depending upon duration of disease i.e. Group I, II, III and IV have duration of disease <2 years, 2-5 years, 5-10 and >10 years respectively. The examination of autonomic nervous system has been carried out with Heart rate, respiratory rate, pulse, temperature and area of excessive sweating or anhidrosis. Conclusion: This study revealed that the neuropathy was directly proportionate to the duration of disease. Parasympathetic activity also showed a gradual deterioration starting earlier in the disease course but progressing, similar to the sympathetic neuropathy with the duration of disease. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index