Frequency and Prevalence of Various Breast Lesions on FNAC and Histopathological Correlation.

Autor: Jain, Atul, Chaturvedi, Smriti, Mourya, Nancy, Agarwal, Shikha
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2022, Vol. 13` Issue 8, p2654-2659, 6p
Abstrakt: Background: Benign as well as malignant breast lesions are quite common in Indian population. The current study was carried out with aim of studying the frequency and prevalence of various breast lesions on FNAC and histopathological correlation. Materials & Methods: 241 patients presenting with palpable breast lump of variable duration in FNAC clinic who were clinically stable patient were subjected to FNAC. Results: There were 188 benign and 38 malignant lesions with size <5 cm, 2 benign and 13 malignant lesions with size 5-10 cm. In 200 benign lesions, right side was involved in 93, left side in 84 and bilateral side in 14 cases. In 51 malignant lesions, right side was involved in 17 and left side in 33. C1 comprises of inadequate in 2, C2 had fibroadenoma in 129, gynacomastia in 19, benign phyloid in 3, granulomatous mastitis in 9, breast abscess in 7, fibrocystic change in 1, fibroadenosis in 2, benign breast disease in 12, lactational mastitis in 1 and duct ectasia in 1 case. C3 comprises of proliferative disease with atypia in 4, C4 suspicious for malignancy in 8 and C5 malignancy in 43 cases. FNAC showed maximum benign lesions (74) in age group 10-20 years followed by 21-30 years (66) and 31-40 years (24). Malignant lesions were maximally seen in age group 41-50 years (15) followed by 51-60 years (13) and 31-40 years (12). Cytological type was benign in 184, atypical in 4, suspicious in 8, malignant in 43 and unsatisfactory in 2 cases. Out of 24 cytological benign lesions, 23 were histologically benign and 1 was malignant. 2 atypical malignant found to be histologically malignant, 1 suspicious malignant found to be malignant and 11 cytological malignant was histologically malignant. Sensitivity of FNAC was 84.2%, specificity was 95.8%, PPV was 94.1% and NPV was 88.4%. Conclusion: FNAC is a rapid, cheap, safe, and effective method for the primary categorization of palpable breast lump. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index