| Autor: |
Makris, Pantelis E., Foka, Zoi, Gerotziafas, Grigoris T., Kioumi, Anna, Pithara, Eleutheria |
| Předmět: |
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| Zdroj: |
Clinical & Applied Thrombosis/Hemostasis; Jul1998, Vol. 4 Issue 3, p167-169, 3p, 1 Chart |
| Abstrakt: |
Thrombocytopenia is a serious situation that causes anxiety in doctors due to its relationship with serious hemorrhagic manifestations. Pseudothrombocytopenia, however, is a situation without clinical interest because it is an in vitro decrease in platelet count. Pseudothrombocytopenia is related to the ethylenediaminetetracetate (EDTA)-dependent exposure of antigenic determinants of platelet membrane glycoproteins gpIIb-IIIa and the subsequent reaction of common antibodies with these receptors. To our knowledge, a similar situation in Greece has not been reported. The main characteristic of pseudothrombocytopenia due to EDTA is that the fall in platelet count is time-dependent and it disappears after the use of anticoagulant other than EDTA (e.g., citrate sodium or heparin). We present seven cases of pseudothrombocytopenia revealed when we used automatic hematologic analyzers and EDTA as an anticoagulant. After the use of another anticoagulant (e.g., citrate sodium) the platelet count in the same hematologic analyzer was normal. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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