Cowden's disease associated with medullary carcinoma and fundic gland polyposis: an unreported association.

Autor: Katsinelos, P., Pilpilidis, I., Dimiropoulos, S., Paroutoglou, G., Tsolkas, P., Kamperis, E., Kapelidis, P., Limenopoulos, B., Pitarokilis, M., Baltagiannis, S.
Předmět:
Zdroj: Surgical Endoscopy & Other Interventional Techniques; Jun2003, Vol. 17 Issue 6, p989-989, 1p
Abstrakt: Cowden's disease (multiple hamartoma syndrome) is characterized by multiple hamartomas of ectodermal, endodermal, and mesodermal origin and an autosomal dominant pattern of inheritance. Multiple orocutaneous hamartomas are associated with involvement of other organ systems including fibrocystic breast disease and breast carcinoma, goiter, thyroid cancer, gastrointestinal polyps, and endometrial carcinoma. The current case report describes a 34-year-old man whose illness was characteristic of Cowden's disease. The specific pattern of gastrointestinal and thyroid involvement, however, was not reported. The patient had extensive glucogenic acanthosis of the esophagus, fundic gland polyposis of the stomach, hyperplastic polyps of the colon, and medullary carcinoma of thyroid gland. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index