| Autor: |
Klepikova, S. G., Yu, V. K., Fomicheva, E. E., Mukhasheva, R. D., Praliev, K. D., Solomin, V. A., Berlin, K. D. |
| Předmět: |
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| Zdroj: |
Chemistry of Heterocyclic Compounds; Oct2003, Vol. 39 Issue 10, p1376-1384, 9p |
| Abstrakt: |
Using the 1H NMR spectroscopic method it has been shown that 7-alkoxyalkyl-3-oxa-7-azabicyclo[3.3.1]nonan-9-ones and 7-alkoxyalkyl-3-oxa-7-azabicyclo[3.3.1]nonanes exist in deuterochloroform solution in a double chair conformation. 7-(3-Butoxypropyl)-3-oxa-7-azabicyclo[3.3.1]nonan-9-ol is a 1:1 mixture of the two stereoisomeric alcohols. One of them exists in a double chair conformation having an equatorial hydroxyl group with relation to the piperidine ring and the other in a chair-boat conformation having an axial hydroxyl group which involves an intramolecular hydrogen bond with the unshared electron pair of the nitrogen atom. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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