IMMUNOGLOBULINS IN DERMATITIS HERPETIFORMIS AND VARIOUS OTHER SKIN DISEASES.

Autor: Fraser, N. G., Dick, Heather M., Crichton, W. B.
Předmět:
Zdroj: British Journal of Dermatology; Feb1969, Vol. 81 Issue 2, p89-95, 7p
Abstrakt: Lowering of the mean IgM-globuIin value and elevation of the mean IgA-globulin value were noted in a group of 21 patients with dermatitis herpetiformis. IgM levels determined before and after dapsone therapy revealed no clear evidence of a dapsone effect on this immunoglobulin. No relationship was noted between the IgM-globulin levels and the intestinal mucosa biopsy grading. Fluctuations in the IgM values were noted and in some patients a fall in this immunoglobulin occurred during an exacerbation of the disease. Immunoglobulin patterns were studied in 7 other skin diseases. The abnormalities noted in psoriasis closely paralleled those found in dermatitis herpetiformis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index