Autor: |
Kouhen, Fadila, Dahbi, Zineb, Afif, Mohammed, Chihabeddine, Meriem, Errafiy, Nadia, Oqbani, Kenza, Omor, Youssef, Elhossini, Amal |
Předmět: |
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Zdroj: |
Journal of Medical Case Reports; 7/19/2023, Vol. 17 Issue 1, p1-5, 5p |
Abstrakt: |
Background: Primary carcinosarcoma of the bladder is a rare and highly aggressive tumor, representing less than 1% of all bladder neoplasms. There is no specific treatment guideline has for carcinosarcoma of the bladder, and majority of published patients was treated exclusively by surgery. Case presentation: We report a case of 65-year-old Moroccan man, presented with macroscopic hematuria, pollakiuria and painful urination. Histological analysis showed a biphasic epithelial and mesenchymal proliferation, with invasion of lamina propria and muscularis, compatible with diagnosis of bladder carcinosarcoma. The patient was treated with cystectomy and adjuvant chemotherapy based on gemcitabin-cisplatin, 18 months after treatment, patient still free of recurrence. Conclusion: Carcinosarcoma of the urinary bladder is a rare and aggressive tumor regardless treatment. A multidisciplinary management based on radical cystectomy and combined adjuvant treatments can improve prognosis. In this work, we suggest to propose adjuvant chemotherapy whenever possible. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
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