องค์ประกอบทางเคมีและฤทธิ์ยับยั้งแอลฟาอะไมเลสและแอลฟากลูโคซิเดส ของสารสกัด งวงตาล

Autor: ฉิรินัง, พรอริยา, วัฒนนภาเกษม, อิศรา, ปรารถนารักษ์, เจิมธง, อินทะนิน, จุติพร, ณะวงษ์, และ ศิริวรรณ
Předmět:
Zdroj: Journal of Science & Technology MSU; May/Jun2023, Vol. 42 Issue 3, p127-136, 10p
Abstrakt: The objectives of this research were to investigate chemical composition and α-amylase and α-glucosidase Inhibitory activities of water and ethanolic crude extracts of Borassus flabellifer L. male flowers. The size of residues was compared by Scanning Electron Microscopy (SEM) technique and elemental contents were compared by Energy Dispersive X-ray Spectroscopy (EDS). The results showed that the main element was carbon (C) following by oxygen (O), chlorine (Cl) and potassium (K), respectively. The particle size of water and ethanolic crude extracts were 70.31 and 78.96 μm, respectively, and the particle size was quite uniform. The determination of phenolic compounds in Borassus flabellifer L. male flowers and water and ethanolic crude extracts showed tannin had the highest content at 712.88, 617.81 and 588.04 mg/kg, respectively, followed by gallic acid, isoquercetin, quercetin, catechin, rutin and apigenin, respectively. These results demonstrated that Borassus flabellifer L. male flowers and crude extracts were good sources of antioxidants. The Inhibitory effect of crude extracts to inhibit α-amylase and α-glucosidase was investigated. Water and ethanolic crude extracts revealed better inhibitory effects for α-glucosidase than the positive control, but the inhibition of α-amylase was lower than the positive control. In addition, the inhibitory effect of water crude extract was better than that of ethanolic extract. Therefore, Borassus flabellifer L. male flowers have potential use in the treatment of diabetes. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index