| Autor: |
Popescu, Daniela-Eugenia, Cristina Jura, Ana Maria, Lungu, Nicoleta, Budisan, Camelia, Ştiube, Dana, Şipoş, Simona, Jura, Mihai, Boia, Mărioara |
| Předmět: |
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| Zdroj: |
Ginecologia.ro; 2023 Supplement, Vol. 11, p36-36, 1/2p |
| Abstrakt: |
Introduction. Considered a highly contagious primary infection, chickenpox, also known as varicella, is one of the biological teratogenic factors in pregnant women. The consequences for the product of conception are correlated with the moment of contact of the infection by the embryo fetus. Thus, the neonatal clinical picture is heterogeneous, consisting of severe congenital abnormalities especially in the nervous system and post-infection sequelae, when the disease is contacted during the first 20 weeks of gestation. Perinatal varicella is based on an epidemiological and clinical diagnosis, the mother presenting with a characteristic rash with vesicular skin lesions before birth, and the newborn’s involvement varying according to the time of maternal infection. Materials and method. We present our experience with a total of nine cases of perinatal varicella in pregnant women diagnosed over a six-week period (1.01.2023-10.02.2023). As a prophylactic measure, in order to decrease the risk of maternal-fetal transmission of the disease, in all cases it was possible to postpone delivery until the fifth day after the onset of the rash. Results. For confirmation or refutation, maternal and neonatal IgM and IgG varicella-zoster virus antibodies were determined. Complete blood count, inflammation markers and cerebral ultrasonography were performed. Newborns were isolated from their mothers and from other newborns. Conclusions. Perinatal varicella presents as a condition that can vary depending on the time of maternal involvement; thus, if the infection occurs between six and 21 days before birth, the newborn’s involvement will be mild. If birth occurs within the first five days of disease onset or the rash appears within the first two days postpartum, 25-50% of newborns may be affected by a severe form of the disease. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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