| Autor: |
Namas, Rajaie, Elarabi, Mohamed, Fayad, Fouad, Ghanem, Aqeel A Muhanna, Al-Herz, Adeeba, Hafiz, Waleed, Joshi, Abhay, Merashli, Mira, Okais, Jad, Uthman, Imad, Essa, Khuloud Saleh, Omair, Mohammed A |
| Předmět: |
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| Zdroj: |
Open Access Rheumatology: Research & Reviews; May2023, Vol. 15, p93-102, 10p |
| Abstrakt: |
There is a significant variation in symptoms and clinical presentation of connective tissue disorders (CTD) associated with interstitial lung disease (ILD) (CTD-ILD). This presents difficulties in the diagnosis and treatment of CTD-ILD. Early detection and treatment of CTD-ILD using a multidisciplinary approach have been shown to enhance patient outcomes. This exercise aims to explore clinical components to develop a screening tool for pulmonologists for early detection of CTD in ILD and to provide a framework for a multidisciplinary approach in managing CTD-ILD. This in turn will lead to early treatment of CTD-ILD in collaboration with rheumatologists. A panel of 12 leading rheumatologists from the Middle East and North Africa (MENA) region met virtually to select the most relevant clinical findings to aid in identifying CTD-ILD. Twelve panellists opted to investigate seven of the most common inflammatory autoimmune disorders. The panel discussed how to improve the early detection of CTD-ILD. Clinical characteristics were categorized, and a nine-item questionnaire was created. A biphasic algorithm was developed to guide early referral to a rheumatologist based on the presence of one of nine clinical features of CTD (Phase 1) or the presence of CTD-specific antibodies (Phase 2). A brief questionnaire has been developed to serve as a simple and practical screening tool for CTD-ILD detection. Additional research is needed to validate and evaluate the tool in longitudinal cohorts. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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