Acute liver failure associated with human adenovirus infection after allogeneic hematopoietic stem cell transplantation.

Autor: Lin, Zhimin, Wu, Yanjun, Zhao, Ye, Wang, Tingjing, Xia, Jing, Qiu, Huiying, Jin, Zhengming, Wu, Depei, Chen, Feng
Předmět:
Zdroj: Annals of Hematology; Aug2023, Vol. 102 Issue 8, p2287-2289, 3p
Abstrakt: Adoptive T cell therapy, an alternative therapy in which virus-specific memory T cells (VST) are injected into the recipient to destroy the virus, is effective at low doses [[9]]. PB mNGS suggested 86,615 reads of HAdV group C. Finally, he was clinically diagnosed as acute severe human adenovirus hepatitis, and acute liver failure (Table 2). Also, the emerging T cell receptor-engineered T cell therapy (TCR-T) can alter donor T cell specificity at the gene level. [Extracted from the article]
Databáze: Complementary Index