| Autor: |
Xue, Qi, Xing, Qijing, Dong, Ling, Guo, Min, Zhang, Xiaoyan, Wei, Xinchun, Jia, Benli, Wang, Yong, Chen, Hong, Hu, Xianwen, Liu, Hong, Zhang, Ye, Wong, Gordon Tin Chun, Huang, Chunxia |
| Předmět: |
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| Zdroj: |
Surgical Endoscopy & Other Interventional Techniques; Aug2023, Vol. 37 Issue 8, p5999-6007, 9p |
| Abstrakt: |
Background: The use of multimodal pharmacological prophylactic regimes has decreased postoperative nausea and vomiting (PONV) in general but it still occurs in over 60% of female patients after bariatric surgery. This study aimed to evaluate the efficacy of ST36 acupoint injection with anisodamine in prevention of PONV among female patients after bariatric surgery. Methods: Ninety patients undergoing laparoscopic sleeve gastrectomy were randomly allocated to anisodamine or control group at the ratio of 2:1. Anisodamine or normal saline was injected into Zusanli (ST36) bilaterally after induction of general anesthesia. The incidence and severity of PONV were assessed during the first 3 postoperative days and at 3 months. The quality of early recovery of anesthesia, gastrointestinal function, sleep quality, anxiety, depression, and complications were also evaluated. Results: Baseline and perioperative characteristics were comparable between two groups. In the anisodamine group, 25 patients (42.4%) experienced vomiting within postoperative 24 h compared with 21 (72.4%) in the control group (relative risk 0.59; 95% confidence interval 0.40–0.85). Time to first rescue antiemetic was 6.5 h in anisodamine group, and 1.7 h in the control group (P = 0.011). Less rescue antiemetic was required during the first 24 h in the anisodamine group (P = 0.024). There were no differences in either postoperative nausea or other recovery characteristics. Conclusions: The addition of ST36 acupoint injection with anisodamine significantly reduced postoperative vomiting without affecting nausea in female patients with obesity undergoing laparoscopic sleeve gastrectomy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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