A Review Article on Synthesis of Different Types of Bioactive Spiropyrazole Derivatives.

Autor:	Farghaly, Thoraya A., Al-Hussain, Sami A., Zaki, Magdi E. A., Al-Qurashi, Nadia T., Alharbi, Salwa S., Muhammad, Zeinab A.
Předmět:	PYRAZOLES HETEROCYCLIC compounds RING formation (Chemistry) VASODILATION INDUSTRIAL applications
Zdroj:	Polycyclic Aromatic Compounds; 2023, Vol. 43 Issue 6, p5639-5734, 96p
Abstrakt:	Pyrazole category with all derivatives have well-known with biological and industrial applications. Pyrazole combined with other cycle (aliphatic or heterocycles) through one carbon atoms afforded spiropyrazoles. This spiropyrazoles characterized with biological importance as antitumor, analgesic, anti-inflammatory, vasodilation, aldosterone antagonistic, antimicrobial, phosphodiesterase, anabolic, androgenic, progestational, and salt-retaining activities. We interested in this review to collect and sort the spiropyrazoles according to their combined rings and illustrated the different methods of synthesis until the middle of 2021. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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