| Autor: |
de Lorimier, L. P., Fan, T. M., Haney, S., Grimm, J. B., Charney, S. C., Clifford, C. A. |
| Předmět: |
|
| Zdroj: |
Veterinary & Comparative Oncology; Mar2005, Vol. 3 Issue 1, p39-39, 1p |
| Abstrakt: |
Megavoltage radiation is considered standard therapy for feline sinonasal neoplasia, but a paucity of published reports and the lack of a staging system based on advanced sectional imaging render accurate prognostication difficult. The aims of this retrospective study on feline sinonasal neoplasia were to adapt or develop a staging system based on advanced imaging, and to further define the prognosis with megavoltage radiation therapy.Medical records were reviewed, and CT images were evaluated by a single radiologist(JBG) and staged using a modified system previously reported for dogs. Further follow-up information was obtained by telephone interviews with the referring veterinarians or owners.Thirty-six cats received megavoltage radiation for sinonasal neoplasia. Carcinomas(n = 17) and lymphomas(n = 16) were most common, followed by sarcomas(n = 3). A majority of immunophenotyped lymphomas were B-cell(89%). Diagnostic CT images were available for review on 33 cats. The stage distribution was as follows: T1(n = 3), T2(n = 11), T3(n = 5), T4(n = 14). Lymphomas were more commonly T2(n = 8) while a majority of carcinomas were T4(n = 8). The median survival times have not yet been reached for any stage or disease subtype. The most common cause for euthanasia was local recurrence(15/19, 79%). Four cats that died of other causes lived between 1,124 and 2,322 days.Feline sinonasal neoplasia is uncommon, with carcinomas and lymphomas being most frequently encountered. Megavoltage radiation therapy appears to offer improved quality and duration of life for most patients, despite advanced staged at diagnosis in a majority. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
