THE DURATION OF QRS COMPLEX AS A PREDICTOR OF ADVERSE CARDIOVASCULAR EVENTS AFTER ACUTE ST-ELEVATION MYOCARDIAL INFARCTION.

Autor: Balenović, Ana, Cankovic, Milenko, Petrović, Ivan
Předmět:
Zdroj: Lijecnicki Vjesnik; 2023 Supplement, Vol. 145, p88-88, 1/2p
Abstrakt: Background: Ischemic heart disease most commonly occurs as a result of atherosclerotic changes in the coronary vessels. An acute form of coronary artery disease is ST-elevation myocardial infarction (STEMI). The duration of QRS complex is one of the ECG parameters whose change in dynamics can indicate the success of PCI as well as the size of the infarct zone. Aim: Evaluation of the width of QRS complex as a predictor of major adverse cardiac events (MACE) in 6 years long follow up. Material and Methods: This study included 200 patients with STEMI. Based on the duration of discomfort two groups were formed (N=100). The duration of the QRS complex was correlated with the duration of discomfort and occurrence of MACE. Results: The survey included 71% of men and 29% of women with an average age of 60.6 ± 11.39. All-cause mortality was 12% (8% cardiovascular, 4% other). MACE occurred in 24.6% of patients. QRS complex width one hour after PCI affects MACE (p<0.025; OR=1.027). The average number of days until cardiovascular death is lower in group B (2187 vs. 2469; p<0.012). ROC analysis showed that the width of QRS complex one hour after PCI is a predictor of MACE (p=0.014; AUC=0.612; cut-off=99.0 msec). The sensitivity is 53.4%, and the specificity is 61.9%. Same parameter has a predictive value for cardiovascular death (p=0.041; AUC= 0.665; cut-off= 99.0 msec), with a sensitivity of 64.3% and specificity of 60.1%. Conclusion: The width of the QRS complex is an independent predictor of MACE. Broadering of QRS complex by one millisecond, one hour after PCI, increases the risk of MACE by 3%. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index