| Autor: |
Hsu, Charlie Chia-Tsong, Fomin, Igor, Wray, Bradley, Brideaux, Adam, Lyons, Duncan, Jaya Kumar, Mahendrah, Watkins, Trevor, Haacke, E Mark, Krings, Timo |
| Zdroj: |
Neuroradiology Journal; Aug2023, Vol. 36 Issue 4, p414-420, 7p |
| Abstrakt: |
Background and purpose: To investigate Susceptibility Weighted Imaging (SWI) signal changes in the draining vein of deep-seated arterio-venous malformations (AVMs) following stereotactic radiosurgery (SRS). Methods and Materials: This is a retrospective study of 32 patients with deep-seated AVMs who were treated with SRS. Pre-SRS treatment and post-SRS treatment MRI were performed at 6, 12, and 24-month intervals. Deep-seated AVMs were classified based on their anatomical location and venous drainage pattern. AVM nidal volume (cm3) was estimated using the ABC/2 method. AV shunting of the AVM draining veins were graded according to its SWI signal intensity: hyperintense (grade III), mixed signal intensity (grade II), hypointense (grade I) and absent (grade 0). Conventional time-of-flight (TOF)-MRA and contrast enhanced (CE)-MRA sequences were performed to document the patency of the vein. Results: Pre-SRS treatment AVM draining veins were either grade III 18/32 (56%) or grade II 14/32 (44%). Using mixed effects analysis, we demonstrate that each month following the SRS treatment nidal volumes decreased at the rate of 0.51 cm3/per month (CI −0.61 to (−0.40)) p =.00. Following the treatment, there was a clinically significant relationship between the signal and nidal volume: signal 0 corresponded with average nidal volume of 1.81 cm3 (CI 1.40–2.21), signal 1 with nidal volume of 2.06 cm3 (CI 1.69–2.44), signal 2 with nidal volume 2.73 cm3 (CI 2.35–3.11) and signal 3 with nidal volume 3.13 cm3 (CI 2.70–3.56) p =.00. Conclusion: Post-SRS AVM draining veins shows a stepwise regression of the SWI signal grades which can be reliably used as a surrogate to monitor the reduction of AV shunting. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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