| Autor: |
Üstündağ, Yasemin, Huysal, Kağan, Kazancı, Elif Güler, Yıldırım, Fatih, Yeşil, Meryem Rümeysa |
| Předmět: |
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| Zdroj: |
Acta Haematologica Polonica; 2023, Vol. 54 Issue 3, p169-175, 7p |
| Abstrakt: |
Introduction: Automated hematology analyzer platelet counts can be performed using either the impedance (PLT-I) method or the fluorescent nucleic acid staining (PLT-O) method. Estimated platelet counts (PLT-E) can be calculated using a digital morphology analyzer by evaluating the peripheral blood smear. Our objective was to compare the platelet values detected on a Mindray BC-6200 device to the PLT-E count on a Mindray MC-80 digital morphology analyzer. Material and methods: Complete blood cell count findings between 1 September and 11 October, 2022 were ob- tained from the data storage units of the devices. We selected two groups of blood: a first group with thrombocyto- penia (n = 49) and a second group that gave an aggregation and/or platelet clumping flag (n = 32). The results of 190 consecutive patients with normal platelet counts, and no aggregation flag, were evaluated as a control group. Pearson’s correlation coefficients, Bland-Altman plots, and paired t-tests were calculated. Results: The plot of the difference between PLT-I and PLT-O counts showed that the mean difference was –43.6 (95%: –17.2 to –69.9); when we compared PLT-O to PLT-E, bias was improved to –6.1 (95%: –18.26 to 6.1) in samples with aggregation and/or clumping flags (Bland-Altman plots). In samples with thrombocytopenia without aggregation and/or clumping, on the Bland-Altman plot, the differences in means were all close to zero, and there were no definite biases. Conclusions: Examining blood samples using the Mindray MC-80 digital morphology analyzer system on samples that show platelet clumps has the potential to improve PLT-I results in day-to-day laboratory routine. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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