Abstrakt: |
Taking advantage of established in vitro melanoma models resistant to BRAFi, MEKi, or dual resistance to BRAFi/MEKi, we demonstrated that Nrf2 was upregulated in melanoma cells resistant to targeted therapy at the post-translational level and that the deubiquitinase DUB3 participated in the control of the Nrf2 protein stability." Keywords: Cancer; Drugs and Therapies; Health and Medicine; Melanoma; Oncology EN Cancer Drugs and Therapies Health and Medicine Melanoma Oncology 1150 1150 1 07/10/23 20230714 NES 230714 2023 JUL 11 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- New study results on melanoma have been published. [Extracted from the article] |