INVESTIGATING THE PREVALENCE OF AUTOIMMUNE DISEASES IN ENDOMETRIOSIS PATIENTS.

Autor: Batu, Sena, Sayın, Sezin, Köse, Ekin Beyza, Yıldırım, Melike Sevde, Kasapoğlu, Elçin, Budak, Oya, Ateş, Sinan, Elter, Koray
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Zdroj: Turkish Medical Student Journal; 2023, Vol. 10 Issue 2, p124-128, 5p
Abstrakt: Aims: This study aims to determine the prevalence of autoimmune diseases in women with endometriosis who were admitted to the Department of Gynecology and Obstetrics, Trakya University Hospital. Methods: The comorbid autoimmune diseases of 231 women older than 18 years diagnosed with endometriosis by surgery and pathology were examined. Considered autoimmune diseases were: Systemic lupus erythematosus, inflammatory bowel disease (Crohn's disease and ulcerative colitis), autoimmune thyroiditis, Addison's disease, rheumatoid arthritis, multiple sclerosis, celiac disease, and Sjogren's syndrome. Results: The mean age of women was 41.94±0.5. The association rate of endometriosis with at least one autoimmune disease was 11.69%. There were 18 patients with autoimmune thyroiditis (7.8%), 9 patients with rheumatoid arthritis (3.9%), 4 patients with ulcerative colitis (1.7%), 2 patients with systemic lupus erythematosus (0.9%), 2 patients with Crohn's disease (0.9%), 1 patient with Addison's disease (0.4%), 1 patient with celiac disease (0.4%), 1 patient with multiple sclerosis (0.4%) and no patients with Sjogren's syndrome. No statistically significant differences were found between the stages of endometriosis in patients with or without autoimmune diseases. Conclusion: To our knowledge, this is the only Turkiye-based study investigating the prevalence of autoimmune diseases in endometriosis patients. We examined the relationship between endometriosis and autoimmune disease depending on the endometriosis stage and patient age, but we could not reach a statistically significant conclusion. However, our data must be analyzed with caution due to the retrospective single-center study design and the small sample size. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index