A case of eosinophilic bronchiolitis after the initiation of immune checkpoint inhibitor.

Autor:	Tamura, Akiko, Hashimoto, Masao, Hosoi, Atsuko, Hojo, Masayuki
Předmět:	THERAPEUTIC use of monoclonal antibodies C-reactive protein IMMUNE checkpoint inhibitors PREDNISOLONE BIOPSY IMMUNOGLOBULINS BRONCHOALVEOLAR lavage CANCER chemotherapy EOSINOPHILIA DYSPNEA NEUTROPHILS BRONCHIOLE diseases COUGH LEUKOCYTE count PULMONARY function tests COMPUTED tomography BREAST tumors RARE diseases BRONCHOSCOPY
Zdroj:	Thoracic Cancer; Jul2023, Vol. 14 Issue 19, p1894-1898, 5p
Abstrakt:	A 50‐year‐old Japanese woman with advanced breast cancer presented with productive cough and dyspnea while she was receiving a sixth cycle of chemotherapy including atezolizumab. Chest computed tomography revealed bronchiolitis and transbronchial lung cryobiopsy revealed eosinophilic bronchiolitis. Corticosteroid therapy successfully resolved her symptoms. Eosinophilic bronchiolitis is a rare but important immune‐related adverse event; herein, we discuss its diagnosis and possible pathophysiology. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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