From unknown poisoning to carbamazepine poisoning.

Autor: Simonovska, Natasha, Chibishev, Andon, Bekarovski, Niko, Babulovska, Aleksandra, Ivanova, Biljana, Naumovski, Kiril, Kostadinovski, Kristin
Předmět:
Zdroj: Emergency Care Journal; 2023, Vol. 19 Issue 2, p20-23, 4p
Abstrakt: In the 2020 annual report of the American Association of Poison Control Centers, 2562 toxic exposures to carbamazepine have been reported, 908 resulted in hospitalization, and among these about 5-6% were life-threatening or resulted in significant disability. A 15-year-old female patient was brought under suspicion of alcohol poisoning. The result of alcoholemia was 11.0 mg/dL and the toxicological screening for THC, opiates, methadone, tramadol, amphetamine, MDMA, cocaine, benzodiazepines, buprenorphine was negative. At admission she was comatose (GCS=6), with metabolic acidosis, hypotension, rare short-term partial seizures, isochoric and later dilated pupils, body temperature was 36.4°C, with oxygen saturation from 89 up to 93%. Toxicological analysis were immediately extended. After three hours of admission, a result was obtained where the plasma concentration for carbamazepine was 167mmol/L. The patient was quickly prepared for hemodialysis which was performed for four hours. After 8 hours of admission the patient woke up with stable vital parameters. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index