| Autor: |
Bolshakova, Valeriya S., Sinegubova, Ekaterina O., Esaulkova, Yana L., Peregudov, Alexander S., Khakina, Ekaterina A., Slesarenko, Nikita A., Shestakov, Alexander F., Zarubaev, Vladimir V., Troshin, Pavel A., Kraevaya, Olga A. |
| Předmět: |
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| Zdroj: |
Chinese Journal of Chemistry; Aug2023, Vol. 41 Issue 15, p1803-1808, 6p |
| Abstrakt: |
Comprehensive Summary: Herein, we present a facile synthesis of amide‐type water‐soluble fullerene derivatives decorated with five residues of amino acids. As compared to the previously developed approaches, the proposed method enables usage of a broad range of amino acids, including those unstable under Friedel‐Crafts reaction conditions. Furthermore, it is fully tolerant to the nature of the sixth addend X in C60R5X precursor compounds and allows one to obtain fullerene derivatives with X=Cl, H, alkyl. The synthesized amide‐type water‐soluble fullerene derivatives demonstrated promising antiviral activities against rimantadine‐resistant influenza А/Puerto Rico/8/34 (Н1N1) virus in vitro. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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