Abstrakt: |
This study is designed to link quantitative data from iron levels and neuroinflammation metabolites obtained from 7T MRI of HD patients, with specific and well-known clinical biofluid markers for iron accumulation, neurodegeneration and neuroinflammation. Keywords: Basal Ganglia Diseases and Conditions; Biomarkers; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Chorea; Cognition Disorders; Dementia; Diagnostics and Screening; Dyskinesias; Health and Medicine; Huntington Disease; Movement Disorders; Nervous System Heredodegenerative Disorders; Neurodegenerative Diseases and Conditions; Neuroinflammation EN Basal Ganglia Diseases and Conditions Biomarkers Brain Diseases and Conditions Central Nervous System Diseases and Conditions Chorea Cognition Disorders Dementia Diagnostics and Screening Dyskinesias Health and Medicine Huntington Disease Movement Disorders Nervous System Heredodegenerative Disorders Neurodegenerative Diseases and Conditions Neuroinflammation 252 252 1 07/03/23 20230707 NES 230707 2023 JUL 8 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Imaging Week -- Fresh data on huntington disease are presented in a new report. Biofluid markers will provide quantitative measures of overall iron accumulation, neurodegeneration and neuroinflammation, while MRI measurements on the other hand will provide quantitative spatial information on brain pathology, neuroinflammation and brain iron accumulation, which will be linked to clinical outcome measures. [Extracted from the article] |